GREM2

Across TCGA cell cohorts, GREM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 975 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GREM2-associated GO terms across cancer lineages are Determination of dorsal/ventral asymmetry, Peripheral nervous system axon ensheathment, and Myelination in peripheral nervous system. Each is linked with GREM2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GREM2-to-partner and partner-to-GREM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Determination of dorsal/ventral asymmetry grouped by GREM2-low versus GREM2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GREM2→partner) and Y-score (partner→GREM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Determination of dorsal/ventral asymmetry →	-0.144	-0.474	.001	.006	3	7
CNS	Peripheral nervous system axon ensheathment →	+0.077	+0.953	<.001	.001	3	6
CNS	Myelination in peripheral nervous system →	+0.077	+0.953	<.001	.001	3	6
SKIN	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.060	+0.435	.001	.001	3	6
BONE	Positive regulation of cell-substrate junction organization →	+0.223	+0.767	<.001	.009	3	5
CNS	Peripheral nervous system development →	+0.085	+0.949	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 975 associations by consensus.

Determination of dorsal/ventral asymmetry by GREM2 expression — BLOOD_Lymphoma

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