GREM1

Across TCGA cell cohorts, GREM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,196 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GREM1-associated GO terms across cancer lineages are Maintenance of protein location, Ureteric bud formation, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with GREM1 in more than 8 cancer types. Because this analysis shows association rather than direction, both GREM1-to-partner and partner-to-GREM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein location grouped by GREM1-low versus GREM1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GREM1→partner) and Y-score (partner→GREM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Maintenance of protein location →	+0.134	+1.289	<.001	.002	3	9
OVARY	Ureteric bud formation →	+1.544	+3.483	<.001	<.001	3	9
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.087	+1.447	<.001	<.001	3	8
LIVER	Negative regulation of cell cycle G1/S phase transition →	+0.146	+6.519	<.001	<.001	3	8
BREAST	Maintenance of protein location in cell →	+0.128	+1.276	<.001	.002	3	8
LIVER	Mesonephric tubule formation →	+1.524	+6.216	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,196 associations by consensus.

Maintenance of protein location by GREM1 expression — BREAST

Explore this box plot interactively →