Across TCGA patient cohorts, GREB1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,760 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GREB1-associated genes across cancer lineages are HDAC5, ACTR10, and CD46. Each is linked with GREB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GREB1-to-partner and partner-to-GREB1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GREB1→partner) and Y-score (partner→GREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HDAC5 →	-0.464	-0.923	<.001	<.001	3	3
COAD	ACTR10 →	+0.602	+1.851	.004	.006	3	3
BRCA	CD46 →	+0.503	+0.609	.007	<.001	3	2
OV	MTERF4 →	-0.303	-0.743	.003	.001	3	2
LSCC	KLHDC3 →	-0.531	-1.194	.008	.002	2	3
OV	FXYD6 →	-0.866	-0.878	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,760 associations by consensus.

Exploration

GREB1 survival (RNA) · tumor vs normal (RNA) · all GREB1 data types