Across TCGA patient cohorts, GREB1 mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GREB1-associated genes across cancer lineages are Cyclin-B1, PDCD4, and RAD51. Each is linked with GREB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GREB1-to-partner and partner-to-GREB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GREB1→partner) and Y-score (partner→GREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.424	+2.070	.001	.001	3	5
UCEC	PDCD4 →	-0.375	-1.378	.001	.005	3	5
COAD	RAD51 →	+0.131	+2.584	.007	.009	3	5
STAD	c-Jun_pS73 →	-0.152	-2.321	.041	.032	3	4
UCEC	ATM →	-0.597	-1.758	<.001	<.001	3	4
COAD	Caspase-7-cleavedD198 →	+1.128	+2.824	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

GREB1 survival (RNA) · tumor vs normal (RNA) · all GREB1 data types