Across TCGA cell cohorts, GREB1 mutation is significantly associated with the RNA expression of many other genes, with 378 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GREB1-associated genes across cancer lineages are AMY1A, TEX55, and PLEKHS1. Each is linked with GREB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GREB1-to-partner and partner-to-GREB1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GREB1→partner) and Y-score (partner→GREB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	AMY1A →	+0.373	+5.000	<.001	.005	3	2
CNS	TEX55 →	+0.017	+3.321	.001	.003	3	2
BLOOD_Leukemia	PLEKHS1 →	+0.068	+3.814	<.001	.002	3	2
BLOOD_Leukemia	TSSK1B →	+0.012	+3.704	<.001	.001	3	2
LARGE_INTESTINE	FBXL4 →	+0.449	+3.169	.003	.009	3	2
LARGE_INTESTINE	MAGEB4 →	+0.007	+2.540	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 378 associations by consensus.

Exploration

GREB1 survival (RNA) · tumor vs normal (RNA) · all GREB1 data types