GRB7

Across TCGA patient cohorts, GRB7 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,017 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRB7-associated proteins across cancer lineages are ERBB2, WIPF2, and XAB2. Each is linked with GRB7 in more than 6 cancer types. Because this analysis shows association rather than direction, both GRB7-to-partner and partner-to-GRB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRB7 versus ERBB2 in BRCA, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRB7→partner) and Y-score (partner→GRB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ERBB2 →	+0.711	+1.040	<.001	<.001	3	7
BRCA	WIPF2 →	+0.509	+1.277	<.001	.004	3	5
LSCC	XAB2 →	+0.257	+0.865	<.001	<.001	3	5
COAD	STAG2 →	+0.212	+0.686	<.001	<.001	3	5
HNSC	ESRP1 →	+0.482	+0.741	<.001	<.001	3	5
LSCC	GTF3C2 →	+0.270	+0.772	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,017 associations by consensus.

GRB7 vs ERBB2 — BRCA

Explore this scatter interactively →