GRB2

Across TCGA patient cohorts, GRB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,413 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRB2-associated proteins across cancer lineages are WBP2, SAMSN1_S23, and NCF2. Each is linked with GRB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GRB2-to-partner and partner-to-GRB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRB2 versus WBP2 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRB2→partner) and Y-score (partner→GRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WBP2 →	+0.609	+0.588	<.001	<.001	3	8
OV	SAMSN1_S23 →	+0.579	+0.385	.001	.007	3	6
COAD	NCF2 →	+0.602	+0.542	<.001	<.001	3	6
GBM	PARVG →	+0.545	+0.341	<.001	<.001	3	6
LUAD	LCP2 →	+0.464	+0.392	<.001	<.001	3	6
LUAD	FCER1G →	+0.758	+0.404	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,413 associations by consensus.

GRB2 vs WBP2 — OV

Explore this scatter interactively →