GRB14

Across TCGA patient cohorts, GRB14 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,682 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GRB14-associated proteins across cancer lineages are GRB14_S372, NELFB, and NELFE. Each is linked with GRB14 in more than 5 cancer types. Because this analysis shows association rather than direction, both GRB14-to-partner and partner-to-GRB14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRB14 versus GRB14_S372 in BRCA, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRB14→partner) and Y-score (partner→GRB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GRB14_S372 →	+1.302	+1.335	<.001	<.001	3	6
LSCC	NELFB →	+0.279	+0.958	<.001	<.001	3	3
LSCC	NELFE →	+0.281	+1.248	<.001	<.001	3	3
LUAD	NFRKB_S228 →	-0.742	-1.051	.002	.004	3	3
BRCA	NISCH_S1284 →	-0.433	-1.034	.005	.005	3	3
LSCC	ORC4 →	+0.249	+0.805	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,682 associations by consensus.

GRB14 vs GRB14_S372 — BRCA

Explore this scatter interactively →