GRB14

Across TCGA patient cohorts, GRB14 protein abundance is significantly associated with the RNA expression of many other genes, with 2,357 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRB14-associated genes across cancer lineages are VTI1B, CKM, and ENO3. Each is linked with GRB14 in more than 2 cancer types. Because this analysis shows association rather than direction, both GRB14-to-partner and partner-to-GRB14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRB14 versus VTI1B in HNSC, with a Pearson correlation of 0.21.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRB14→partner) and Y-score (partner→GRB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VTI1B →	+0.512	+0.626	<.001	.003	3	2
HNSC	CKM →	+3.647	+0.687	<.001	.001	3	2
HNSC	ENO3 →	+1.668	+0.518	.004	.009	3	2
HNSC	RBM24 →	+1.332	+0.517	.004	.001	3	2
HNSC	TNNC1 →	+2.138	+0.384	.001	.002	3	2
HNSC	MED28 →	+0.479	+0.668	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,357 associations by consensus.

GRB14 vs VTI1B — HNSC

Explore this scatter interactively →