GRB14

Across TCGA cell cohorts, GRB14 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,955 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GRB14-associated GO terms across cancer lineages are Response to mechanical stimulus, Methylation, and Macromolecule methylation. Each is linked with GRB14 in more than 6 cancer types. Because this analysis shows association rather than direction, both GRB14-to-partner and partner-to-GRB14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to mechanical stimulus grouped by GRB14-low versus GRB14-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRB14→partner) and Y-score (partner→GRB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to mechanical stimulus →	-0.068	-1.727	.005	.002	3	7
LUNG_SCLC	Methylation →	+0.045	+1.517	<.001	<.001	2	7
BONE	Macromolecule methylation →	+0.062	+1.029	.003	.005	2	7
LIVER	Lacrimal gland development →	+1.013	+2.580	.008	.005	3	6
LUNG_SCLC	Protein methylation →	+0.070	+1.351	.001	.001	3	5
LUNG_SCLC	Protein alkylation →	+0.070	+1.351	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,955 associations by consensus.

Response to mechanical stimulus by GRB14 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →