GRB10

Across TCGA patient cohorts, GRB10 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,259 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GRB10-associated proteins across cancer lineages are GRB10_S104, GRB10_S150, and MAP1B. Each is linked with GRB10 in more than 9 cancer types. Because this analysis shows association rather than direction, both GRB10-to-partner and partner-to-GRB10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRB10 versus GRB10_S104 in LUAD, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRB10→partner) and Y-score (partner→GRB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GRB10_S104 →	+0.996	+0.876	<.001	<.001	3	10
GBM	GRB10_S150 →	+1.404	+1.664	.002	.001	3	7
LSCC	MAP1B →	+0.823	+0.613	.001	.001	3	5
BRCA	SRP68 →	-0.162	-0.548	.001	<.001	3	4
HNSC	DEF6 →	-0.301	-0.916	<.001	<.001	3	4
GBM	ERBB3_S982 →	-0.825	-0.931	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,259 associations by consensus.

GRB10 vs GRB10_S104 — LUAD

Explore this scatter interactively →