Across TCGA patient cohorts, GRAPL RNA expression is significantly associated with the go_rna of many other GO terms, with 7,104 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GRAPL-associated GO terms across cancer lineages are Regulation of endothelial cell migration, Blood vessel endothelial cell migration, and Negative regulation of epithelial cell migration. Each is linked with GRAPL in more than 27 cancer types. Because this analysis shows association rather than direction, both GRAPL-to-partner and partner-to-GRAPL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAPL→partner) and Y-score (partner→GRAPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Regulation of endothelial cell migration →	+0.080	+0.424	.001	<.001	2	28
SCLC	Blood vessel endothelial cell migration →	+0.151	+0.517	<.001	<.001	3	27
SCLC	Negative regulation of epithelial cell migration →	+0.082	+0.358	<.001	.001	3	26
SCLC	Regulation of blood vessel endothelial cell migration →	+0.077	+0.414	<.001	<.001	3	26
SCLC	Protein autophosphorylation →	+0.073	+0.488	<.001	<.001	3	26
SCLC	Vasculogenesis →	+0.089	+0.384	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,104 associations by consensus.

Exploration

GRAPL survival (RNA) · tumor vs normal (RNA) · all GRAPL data types