Across TCGA cell cohorts, GRAPL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,362 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GRAPL-associated GO terms across cancer lineages are Regulation of cell fate specification, Establishment of RNA localization, and Intermembrane lipid transfer. Each is linked with GRAPL in more than 7 cancer types. Because this analysis shows association rather than direction, both GRAPL-to-partner and partner-to-GRAPL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAPL→partner) and Y-score (partner→GRAPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of cell fate specification →	+0.167	+2.481	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.076	+0.074	.001	.008	1	8
SOFT_TISSUE	Intermembrane lipid transfer →	+0.089	+0.339	<.001	.006	3	6
OESOPHAGUS	Negative regulation of calcium ion export across plasma membrane →	+0.056	+0.214	.009	.002	3	6
OESOPHAGUS	Olefinic compound metabolic process →	-0.135	-0.253	<.001	.004	3	6
BLOOD_Lymphoma	Regulation of DNA-templated transcription initiation →	+0.044	+2.069	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,362 associations by consensus.

Exploration

GRAPL survival (RNA) · tumor vs normal (RNA) · all GRAPL data types