GRAMD4P7

Across TCGA pan-cancer cohorts, GRAMD4P7 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GRAMD4P7’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where GRAMD4P7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GRAMD4P7 is over-expressed in tumor.

BRCA, LUAD, and THCA are the cancer types where GRAMD4P7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GRAMD4P7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	+0.634	<.001	6	view →
LUAD	Female	III,IV	+0.068	.019	5	view →
THCA	All	All	+0.101	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

GRAMD4P7–BRCA

Open the BRCA breakdown →