GRAMD4P3

Across TCGA patient cohorts, GRAMD4P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,536 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GRAMD4P3-associated GO terms across cancer lineages are DNA conformation change, Regulation of chromosome segregation, and Regulation of sister chromatid segregation. Each is linked with GRAMD4P3 in more than 15 cancer types. Because this analysis shows association rather than direction, both GRAMD4P3-to-partner and partner-to-GRAMD4P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA conformation change grouped by GRAMD4P3-low versus GRAMD4P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD4P3→partner) and Y-score (partner→GRAMD4P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA conformation change →	+0.070	+0.168	<.001	<.001	3	16
ESCA	Regulation of chromosome segregation →	+0.089	+0.254	<.001	<.001	3	16
ESCA	Regulation of sister chromatid segregation →	+0.085	+0.233	<.001	<.001	3	16
ESCA	Sister chromatid segregation →	+0.093	+0.231	<.001	<.001	3	16
ESCA	Positive regulation of DNA metabolic process →	+0.071	+0.248	<.001	<.001	2	16
STAD	Mitotic spindle assembly →	+0.076	+0.185	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,536 associations by consensus.

DNA conformation change by GRAMD4P3 expression — STAD

Explore this box plot interactively →