GRAMD4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GRAMD4 protein abundance is significantly associated with the RNA expression of many other genes, with 8,913 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRAMD4-associated genes across cancer lineages are CCNB1IP1, TMCO6, and ZNF572. Each is linked with GRAMD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRAMD4-to-partner and partner-to-GRAMD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD4 versus CCNB1IP1 in UCEC, with a Pearson correlation of -0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD4→partner) and Y-score (partner→GRAMD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCCNB1IP1 →-0.763-0.432.002<.00135
OVTMCO6 →-0.602-0.357.001.00934
UCECZNF572 →-0.874-0.395.002.00334
LSCCSNHG4 →-0.799-0.288.001.00434
UCECDHX35 →-0.467-0.357.002.00133
UCECPDCD5 →-1.129-0.467<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,913 associations by consensus.

GRAMD4 vs CCNB1IP1 — UCEC

Per-sample scatter of GRAMD4 vs CCNB1IP1 in UCEC (Pearson r = -0.25).

Explore this scatter interactively →

Exploration