GRAMD4

Across TCGA patient cohorts, GRAMD4 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,949 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRAMD4-associated proteins across cancer lineages are CLCC1, EXOSC3, and GRAMD4_S28. Each is linked with GRAMD4 in more than 5 cancer types. Because this analysis shows association rather than direction, both GRAMD4-to-partner and partner-to-GRAMD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD4 versus CLCC1 in PDAC, with a Pearson correlation of 0.60.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD4→partner) and Y-score (partner→GRAMD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CLCC1 →	+0.452	+0.363	<.001	<.001	3	6
UCEC	EXOSC3 →	-0.394	-0.600	<.001	<.001	3	6
CCRCC	GRAMD4_S28 →	+1.638	+1.022	<.001	<.001	3	6
PDAC	TMEM19 →	+0.704	+0.417	<.001	<.001	3	6
UCEC	EXOSC7 →	-0.261	-0.491	<.001	<.001	3	5
BRCA	GOLGB1 →	+0.408	+0.466	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,949 associations by consensus.

GRAMD4 vs CLCC1 — PDAC

Explore this scatter interactively →