GRAMD2B

Across TCGA patient cohorts, GRAMD2B protein abundance is significantly associated with the RNA expression of many other genes, with 8,256 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRAMD2B-associated genes across cancer lineages are PON2, TSPAN1, and BBOX1. Each is linked with GRAMD2B in more than 3 cancer types. Because this analysis shows association rather than direction, both GRAMD2B-to-partner and partner-to-GRAMD2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD2B versus PON2 in COAD, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD2B→partner) and Y-score (partner→GRAMD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PON2 →	+0.856	+0.557	.003	.001	3	4
OV	TSPAN1 →	+1.609	+0.474	.001	<.001	3	4
BRCA	BBOX1 →	+2.121	+0.649	<.001	<.001	3	4
LSCC	MVP →	+0.605	+0.454	.002	.007	3	4
GBM	ALDH7A1 →	+0.802	+0.616	<.001	<.001	3	4
BRCA	CP →	+1.789	+0.443	.004	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,256 associations by consensus.

GRAMD2B vs PON2 — COAD

Explore this scatter interactively →