GRAMD2B

Across TCGA cell cohorts, GRAMD2B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GRAMD2B-associated genes across cancer lineages are PTCHD1, OR10G6, and EFNA2. Each is linked with GRAMD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both GRAMD2B-to-partner and partner-to-GRAMD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTCHD1 grouped by GRAMD2B-low versus GRAMD2B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD2B→partner) and Y-score (partner→GRAMD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PTCHD1 →	+0.537	+3.455	<.001	.002	3	1
BLOOD_Leukemia	OR10G6 →	+0.012	+4.247	<.001	.004	3	1
BLOOD_Leukemia	EFNA2 →	+0.449	+3.906	<.001	.001	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

PTCHD1 by GRAMD2B expression — BLOOD_Leukemia

Explore this box plot interactively →