GRAMD2A

Across TCGA patient cohorts, GRAMD2A protein abundance is significantly associated with the RNA expression of many other genes, with 2,874 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRAMD2A-associated genes across cancer lineages are ITIH6, AGTR1, and ARHGAP29. Each is linked with GRAMD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both GRAMD2A-to-partner and partner-to-GRAMD2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD2A versus ITIH6 in UCEC, with a Pearson correlation of 0.99.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD2A→partner) and Y-score (partner→GRAMD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ITIH6 →	+1.045	+1.714	.005	.005	3	2
LSCC	AGTR1 →	+0.250	+0.416	.006	.002	3	2
LSCC	ARHGAP29 →	+0.666	+0.610	.002	.004	3	2
LSCC	TAF4B →	-0.418	-0.480	.008	.004	3	2
LUAD	PRTG →	+0.889	+0.752	<.001	<.001	3	2
LUAD	SHE →	+0.852	+0.517	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,874 associations by consensus.

GRAMD2A vs ITIH6 — UCEC

Explore this scatter interactively →