GRAMD2A

Across TCGA patient cohorts, GRAMD2A protein abundance is significantly associated with the protein abundance of many other proteins, with 4,200 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRAMD2A-associated proteins across cancer lineages are ANAPC16, ACAP2, and CRACDL_S646. Each is linked with GRAMD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both GRAMD2A-to-partner and partner-to-GRAMD2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD2A versus ANAPC16 in LSCC, with a Pearson correlation of -0.36.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD2A→partner) and Y-score (partner→GRAMD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANAPC16 →	-0.191	-0.493	<.001	.002	3	2
LSCC	ACAP2 →	-0.257	-0.433	.004	.001	3	2
LSCC	CRACDL_S646 →	+0.912	+0.884	.003	<.001	3	2
LUAD	CRYM →	+1.344	+0.796	<.001	<.001	3	2
LUAD	CTSH →	+0.523	+0.544	.004	.001	3	2
LSCC	CXCL17 →	+0.763	+0.766	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,200 associations by consensus.

GRAMD2A vs ANAPC16 — LSCC

Explore this scatter interactively →