GRAMD2A

Across TCGA cell cohorts, GRAMD2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,229 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible GRAMD2A-associated GO terms across cancer lineages are Establishment of protein localization to membrane, Response to indole-3-methanol, and Negative regulation of mRNA catabolic process. Each is linked with GRAMD2A in more than 10 cancer types. Because this analysis shows association rather than direction, both GRAMD2A-to-partner and partner-to-GRAMD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to membrane grouped by GRAMD2A-low versus GRAMD2A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD2A→partner) and Y-score (partner→GRAMD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Establishment of protein localization to membrane →	+0.039	+0.832	<.001	<.001	3	11
BREAST	Response to indole-3-methanol →	+0.201	+2.163	<.001	<.001	3	10
BREAST	Negative regulation of mRNA catabolic process →	+0.053	+1.684	<.001	<.001	3	9
KIDNEY	Regulation of myoblast fusion →	+0.092	+0.910	.001	.004	2	10
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.069	+0.745	.001	.003	3	9
KIDNEY	Endosome organization →	+0.069	+0.964	.004	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,229 associations by consensus.

Establishment of protein localization to membrane by GRAMD2A expression — LARGE_INTESTINE

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