GRAMD1A

Across TCGA patient cohorts, GRAMD1A RNA expression is significantly associated with the protein abundance of many other proteins, with 7,308 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRAMD1A-associated proteins across cancer lineages are GRAMD1A_S267, TOP2B, and PLEKHG2. Each is linked with GRAMD1A in more than 4 cancer types. Because this analysis shows association rather than direction, both GRAMD1A-to-partner and partner-to-GRAMD1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD1A versus GRAMD1A_S267 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD1A→partner) and Y-score (partner→GRAMD1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GRAMD1A_S267 →	+0.667	+0.748	<.001	<.001	3	5
GBM	TOP2B →	+0.251	+0.242	.002	.001	3	4
LUAD	PLEKHG2 →	+0.342	+0.486	<.001	.004	3	4
OV	C1QA →	+0.664	+0.727	.002	.004	3	3
OV	C1R →	+0.594	+0.750	<.001	<.001	3	3
OV	C1S →	+0.480	+0.787	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,308 associations by consensus.

GRAMD1A vs GRAMD1A_S267 — LSCC

Explore this scatter interactively →