GPX8

Across TCGA patient cohorts, GPX8 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,563 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPX8-associated proteins across cancer lineages are SERPINH1, COPZ2, and P3H1. Each is linked with GPX8 in more than 9 cancer types. Because this analysis shows association rather than direction, both GPX8-to-partner and partner-to-GPX8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPX8 versus SERPINH1 in GBM, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPX8→partner) and Y-score (partner→GPX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINH1 →	+0.657	+1.162	<.001	<.001	3	10
OV	COPZ2 →	+0.817	+0.814	<.001	<.001	3	10
BRCA	P3H1 →	+0.701	+1.245	<.001	<.001	3	9
GBM	P4HA2 →	+0.801	+0.934	<.001	<.001	3	9
GBM	PLOD2 →	+0.945	+1.364	<.001	<.001	3	9
CCRCC	PPIC →	+0.900	+0.976	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,563 associations by consensus.

GPX8 vs SERPINH1 — GBM

Explore this scatter interactively →