GPX8

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPX8 protein abundance is significantly associated with the RNA expression of many other genes, with 17,041 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPX8-associated genes across cancer lineages are MRC2, FN1, and GFPT2. Each is linked with GPX8 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPX8-to-partner and partner-to-GPX8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPX8 versus MRC2 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPX8→partner) and Y-score (partner→GPX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMRC2 →+1.208+0.655<.001<.00139
COADFN1 →+2.109+0.392<.001<.00139
CCRCCGFPT2 →+1.464+0.487<.001<.00139
OVPODNL1 →+1.241+0.650<.001<.00139
OVCOL6A2 →+1.390+0.587<.001<.00139
OVADAM12 →+1.851+0.811<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,041 associations by consensus.

GPX8 vs MRC2 — OV

Per-sample scatter of GPX8 vs MRC2 in OV (Pearson r = 0.42).

Explore this scatter interactively →

Exploration