GPX7

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPX7 protein abundance is significantly associated with the RNA expression of many other genes, with 12,767 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GPX7-associated genes across cancer lineages are COL5A1, FSTL1, and POSTN. Each is linked with GPX7 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPX7-to-partner and partner-to-GPX7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPX7 versus COL5A1 in OV, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPX7→partner) and Y-score (partner→GPX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCOL5A1 →+1.996+0.732<.001<.00139
OVFSTL1 →+1.143+0.563<.001<.00139
OVPOSTN →+3.291+0.724<.001<.00139
OVCOL3A1 →+2.164+0.779<.001<.00139
OVLINC01614 →+3.259+0.761<.001<.00139
GBMCOL1A1 →+2.785+0.548<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,767 associations by consensus.

GPX7 vs COL5A1 — OV

Per-sample scatter of GPX7 vs COL5A1 in OV (Pearson r = 0.64).

Explore this scatter interactively →

Exploration