Across TCGA cell cohorts, GPX5 RNA expression is significantly associated with the go_rna of many other GO terms, with 321 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GPX5-associated GO terms across cancer lineages are Regulation of intrinsic apoptotic signaling pathway, Muscle cell proliferation, and Negative regulation of transporter activity. Each is linked with GPX5 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPX5-to-partner and partner-to-GPX5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPX5→partner) and Y-score (partner→GPX5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of intrinsic apoptotic signaling pathway →	+0.065	+0.032	<.001	.009	3	3
LIVER	Muscle cell proliferation →	+0.166	+0.073	.001	.008	3	2
OVARY	Negative regulation of transporter activity →	-0.085	-0.008	.006	.006	3	2
OESOPHAGUS	Negative regulation of RIG-I signaling pathway →	+0.139	+0.004	.001	.009	3	2
BLOOD_Lymphoma	Negative regulation of peptidase activity →	+0.646	+0.032	.008	.009	3	2
BLOOD_Lymphoma	Regulation of macrophage derived foam cell differentiation →	+0.090	+0.032	.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 321 associations by consensus.

Exploration

GPX5 survival (RNA) · tumor vs normal (RNA) · all GPX5 data types