GPSM3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPSM3 mutation is significantly associated with the RNA expression of many other genes, with 126 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GPSM3-associated genes across cancer lineages are RNU6-1052P, RNU6-492P, and RNU6-340P. Each is linked with GPSM3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPSM3-to-partner and partner-to-GPSM3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPSM3→partner) and Y-score (partner→GPSM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNU6-1052P →+0.288+7.954<.001.00833
HNSCRNU6-492P →+0.478+7.954<.001.00832
STADRNU6-340P →+0.686+4.139.001.00432
STADRNU6-867P →+0.621+3.736<.001.00832
STADRNU2-3P →+0.323+4.195.003.00432
STADUBE2V1P10 →+0.159+3.929.006.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 126 associations by consensus.

Exploration