GPSM2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPSM2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,851 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPSM2-associated genes across cancer lineages are MIR4698, KRT14, and SLC25A5P2. Each is linked with GPSM2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPSM2-to-partner and partner-to-GPSM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPSM2 versus MIR4698 in LSCC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPSM2→partner) and Y-score (partner→GPSM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMIR4698 →-1.240-0.448.001.00333
HNSCKRT14 →+1.656+0.342<.001<.00132
COADSLC25A5P2 →-0.582-0.367.001.00132
HNSCNUS1P1 →-0.714-0.456.005<.00132
LSCCTRGV7 →-0.663-0.481<.001.00132
HNSCHSPD1P12 →-0.465-0.311.007.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,851 associations by consensus.

GPSM2 vs MIR4698 — LSCC

Per-sample scatter of GPSM2 vs MIR4698 in LSCC (Pearson r = -0.38).

Explore this scatter interactively →

Exploration