GPSM1

Across TCGA pan-cancer cohorts, GPSM1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GPSM1 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher GPSM1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GPSM1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where GPSM1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.810	0.949	.009	18	view →
LUAD	DFS	Tertile	All	0.668	1.000	.008	5	view →
CCRCC	DFS	Tertile	All	0.873	0.506	.020	5	view →
HNSC	DFS	Quartile	IV	0.982	0.695	.032	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GPSM1–LSCC (OS)

Open the LSCC breakdown →