GPSM1

Across TCGA cell cohorts, GPSM1 mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPSM1-associated genes across cancer lineages are PHF24, ENPP6, and GPR27. Each is linked with GPSM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPSM1-to-partner and partner-to-GPSM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHF24 grouped by GPSM1-low versus GPSM1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPSM1→partner) and Y-score (partner→GPSM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PHF24 →	+0.078	+3.748	.004	.001	3	2
LARGE_INTESTINE	ENPP6 →	+0.028	+2.793	.003	.002	3	1
LARGE_INTESTINE	GPR27 →	+0.753	+3.424	.003	.006	3	1
LARGE_INTESTINE	RXFP1 →	+0.126	+2.938	.002	.003	3	1
LARGE_INTESTINE	SNTG2 →	+0.127	+2.467	.001	.008	3	1
LARGE_INTESTINE	SPEM2 →	+0.041	+2.404	.004	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

PHF24 by GPSM1 expression — LARGE_INTESTINE

Explore this box plot interactively →