GPS1

Across TCGA cell cohorts, GPS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,834 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPS1-associated GO terms across cancer lineages are DNA strand elongation involved in DNA replication, Regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with GPS1 in more than 14 cancer types. Because this analysis shows association rather than direction, both GPS1-to-partner and partner-to-GPS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation involved in DNA replication grouped by GPS1-low versus GPS1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPS1→partner) and Y-score (partner→GPS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA strand elongation involved in DNA replication →	+0.165	+0.596	.003	.005	3	15
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.135	+0.567	<.001	<.001	3	15
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.213	+0.955	<.001	<.001	3	15
BONE	Mitotic DNA replication →	+0.203	+0.758	<.001	<.001	3	14
STOMACH	Positive regulation of mitotic cytokinesis →	+0.159	+0.737	<.001	.001	3	14
URINARY_TRACT	Protein-containing complex disassembly →	+0.071	+0.943	<.001	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,834 associations by consensus.

DNA strand elongation involved in DNA replication by GPS1 expression — BONE

Explore this box plot interactively →