Across TCGA patient cohorts, GPRIN3 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPRIN3-associated genes across cancer lineages are Bak, PKC-b-II_pS660, and Akt. Each is linked with GPRIN3 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPRIN3-to-partner and partner-to-GPRIN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRIN3→partner) and Y-score (partner→GPRIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Bak →	+0.230	+1.906	.007	.015	3	5
UCEC	PKC-b-II_pS660 →	-0.267	-1.514	.004	.015	3	4
LUAD	Akt →	-0.663	-3.169	<.001	.019	3	3
LUAD	Stathmin →	+0.259	+3.169	.003	.018	2	4
UCEC	PDCD4 →	-0.488	-2.312	.002	.005	3	3
UCEC	PKC-delta_pS664 →	-0.091	-1.807	.025	.024	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration

GPRIN3 survival (RNA) · tumor vs normal (RNA) · all GPRIN3 data types