Across TCGA patient cohorts, GPRIN2 protein abundance is significantly associated with the RNA expression of many other genes, with 774 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPRIN2-associated genes across cancer lineages are BTC, EIF3L, and RPL3. Each is linked with GPRIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPRIN2-to-partner and partner-to-GPRIN2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRIN2→partner) and Y-score (partner→GPRIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BTC →	+1.254	+0.436	<.001	<.001	3	2
OV	EIF3L →	+1.058	+0.380	.008	.008	3	1
OV	RPL3 →	+0.942	+0.379	.001	.008	3	1
OV	DHRS2 →	+0.801	+0.379	.002	.008	3	1
OV	SLC25A15 →	-0.505	-0.377	.008	.009	3	1
OV	KCNA7 →	-0.105	-0.478	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 774 associations by consensus.

Exploration

GPRIN2 survival (RNA) · tumor vs normal (RNA) · all GPRIN2 data types