GPRIN2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPRIN2 mutation is significantly associated with the RNA expression of many other genes, with 1,763 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPRIN2-associated genes across cancer lineages are OR4C45, OR8H1, and SNORD114-11. Each is linked with GPRIN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPRIN2-to-partner and partner-to-GPRIN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRIN2→partner) and Y-score (partner→GPRIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAOR4C45 →+0.039+7.640<.001.00933
THCAOR8H1 →+0.124+7.962<.001.00732
THCASNORD114-11 →+0.608+7.962<.001.00732
THCARNU1-101P →+0.410+7.962<.001.00732
THCAUBE2D3P4 →+0.149+7.962<.001.00732
THCAOR4A9P →+0.199+7.962<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,763 associations by consensus.

Exploration