Across TCGA patient cohorts, GPRIN2 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPRIN2-associated genes across cancer lineages are Annexin_VII, CD31, and eIF4E. Each is linked with GPRIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPRIN2-to-partner and partner-to-GPRIN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRIN2→partner) and Y-score (partner→GPRIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Annexin_VII →	-0.157	-3.321	.044	.010	3	1
SKCM	CD31 →	-0.196	-3.000	.018	.035	2	2
UCEC	eIF4E →	+0.213	+3.169	.036	.019	3	1
UCEC	GSK-3a-b_pS21_S9 →	+0.463	+3.009	.024	.019	3	1
UCEC	Heregulin →	-0.189	-3.169	.001	.019	3	1
UCEC	JNK2 →	+0.268	+2.834	.005	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

GPRIN2 survival (RNA) · tumor vs normal (RNA) · all GPRIN2 data types