GPRIN1

Across TCGA patient cohorts, GPRIN1 mutation is significantly associated with the RNA expression of many other genes, with 3,899 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPRIN1-associated genes across cancer lineages are RNU1-17P, DUTP3, and LINC02794. Each is linked with GPRIN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPRIN1-to-partner and partner-to-GPRIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by GPRIN1-low versus GPRIN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRIN1→partner) and Y-score (partner→GPRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-17P →	+0.132	+1.935	.004	.006	3	4
SARC	DUTP3 →	+0.121	+4.778	<.001	.006	3	4
LGG	LINC02794 →	+0.065	+4.711	<.001	.003	3	3
CESC	MED15P6 →	+0.446	+5.786	<.001	<.001	3	2
CESC	NF1P10 →	+0.362	+5.569	<.001	.002	3	2
UCEC	NDUFAF2 →	+0.492	+2.000	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,899 associations by consensus.

RNU1-17P by GPRIN1 expression — UCEC

Explore this box plot interactively →