GPRIN1

Across TCGA cell cohorts, GPRIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,481 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPRIN1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Microtubule cytoskeleton organization involved in mitosis, and Protein-DNA complex organization. Each is linked with GPRIN1 in more than 13 cancer types. Because this analysis shows association rather than direction, both GPRIN1-to-partner and partner-to-GPRIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by GPRIN1-low versus GPRIN1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRIN1→partner) and Y-score (partner→GPRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA-templated transcription initiation →	+0.070	+1.154	<.001	<.001	3	14
SKIN	Microtubule cytoskeleton organization involved in mitosis →	+0.082	+0.767	.001	.006	3	13
UPPER_AERODIGESTIVE_TRACT	Protein-DNA complex organization →	+0.056	+1.023	<.001	<.001	3	13
BREAST	Regulation of chromosome organization →	+0.070	+0.991	.003	<.001	3	12
STOMACH	Regulation of sister chromatid segregation →	+0.132	+1.726	<.001	<.001	3	12
STOMACH	Regulation of chromosome segregation →	+0.137	+1.491	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,481 associations by consensus.

DNA-templated transcription initiation by GPRIN1 expression — PANCREAS

Explore this box plot interactively →