GPRC6A

Across TCGA patient cohorts, GPRC6A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,615 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GPRC6A-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, NADH dehydrogenase complex assembly, and Cellular respiration. Each is linked with GPRC6A in more than 14 cancer types. Because this analysis shows association rather than direction, both GPRC6A-to-partner and partner-to-GPRC6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by GPRC6A-low versus GPRC6A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC6A→partner) and Y-score (partner→GPRC6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial respiratory chain complex assembly →	+0.067	+0.111	<.001	.002	3	15
ESCA	NADH dehydrogenase complex assembly →	+0.053	+0.155	<.001	<.001	3	15
ESCA	Cellular respiration →	+0.070	+0.197	<.001	<.001	3	15
STAD	Regulation of SNARE complex assembly →	+0.058	+0.134	<.001	<.001	3	14
STAD	Establishment of protein localization to membrane →	+0.086	+0.194	<.001	<.001	2	15
STAD	ATP synthesis coupled electron transport →	+0.105	+0.174	<.001	.004	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,615 associations by consensus.

Mitochondrial respiratory chain complex assembly by GPRC6A expression — STAD

Explore this box plot interactively →