GPRC6A

Across TCGA cell cohorts, GPRC6A RNA expression is significantly associated with the go_rna of many other GO terms, with 301 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPRC6A-associated GO terms across cancer lineages are Regulation of calcium ion import, Monosaccharide metabolic process, and Negative regulation of meiotic cell cycle. Each is linked with GPRC6A in more than 2 cancer types. Because this analysis shows association rather than direction, both GPRC6A-to-partner and partner-to-GPRC6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of calcium ion import grouped by GPRC6A-low versus GPRC6A-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC6A→partner) and Y-score (partner→GPRC6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of calcium ion import →	-0.122	-0.067	<.001	.008	3	3
SKIN	Monosaccharide metabolic process →	+0.045	+0.022	<.001	.007	3	3
LUNG_NSCLC_LUSC	Negative regulation of meiotic cell cycle →	-0.086	-0.044	.007	.005	3	2
LUNG_NSCLC_LUSC	Mitochondrion organization →	+0.047	+0.068	.002	.005	3	2
BLOOD_Myeloma	Hexose metabolic process →	+0.050	+0.076	.009	.007	3	2
BLOOD_Myeloma	Dermatan sulfate proteoglycan metabolic process →	+0.098	+0.126	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 301 associations by consensus.

Regulation of calcium ion import by GPRC6A expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →