GPRC5B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPRC5B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,449 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPRC5B-associated proteins across cancer lineages are GPRC5B_S354, TLN2, and UCHL1. Each is linked with GPRC5B in more than 8 cancer types. Because this analysis shows association rather than direction, both GPRC5B-to-partner and partner-to-GPRC5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPRC5B versus GPRC5B_S354 in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5B→partner) and Y-score (partner→GPRC5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGPRC5B_S354 →+1.092+1.330<.001<.00139
HNSCTLN2 →+0.597+0.955<.001<.00135
HNSCUCHL1 →+1.435+0.914<.001<.00134
OVRPS6KA1 →-0.315-0.960<.001<.00134
HNSCNFIB →+0.648+0.824<.001<.00134
GBMREEP4_S152 →-0.522-0.774<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,449 associations by consensus.

GPRC5B vs GPRC5B_S354 — UCEC

Per-sample scatter of GPRC5B vs GPRC5B_S354 in UCEC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration