GPRC5B

Across TCGA patient cohorts, GPRC5B protein abundance is significantly associated with the RNA expression of many other genes, with 4,474 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPRC5B-associated genes across cancer lineages are KAT2B, GIPR, and KNOP1. Each is linked with GPRC5B in more than 2 cancer types. Because this analysis shows association rather than direction, both GPRC5B-to-partner and partner-to-GPRC5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPRC5B versus KAT2B in GBM, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5B→partner) and Y-score (partner→GPRC5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KAT2B →	+0.493	+0.308	<.001	<.001	3	3
LSCC	GIPR →	-0.471	-0.453	.007	.003	3	2
OV	KNOP1 →	+0.684	+0.507	<.001	<.001	3	2
BRCA	LRRC46 →	-1.858	-1.082	.001	.003	3	2
OV	MPP7 →	+0.967	+0.558	<.001	<.001	3	2
OV	SNCG →	+1.641	+0.348	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,474 associations by consensus.

GPRC5B vs KAT2B — GBM

Explore this scatter interactively →