GPRC5A

Across TCGA patient cohorts, GPRC5A RNA expression is significantly associated with the protein abundance of many other proteins, with 18,457 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPRC5A-associated proteins across cancer lineages are GPRC5A_S301, GPRC5A_S345, and C1orf116. Each is linked with GPRC5A in more than 7 cancer types. Because this analysis shows association rather than direction, both GPRC5A-to-partner and partner-to-GPRC5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPRC5A versus GPRC5A_S301 in GBM, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5A→partner) and Y-score (partner→GPRC5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GPRC5A_S301 →	+1.339	+1.336	<.001	<.001	3	8
PDAC	GPRC5A_S345 →	+1.165	+1.029	<.001	<.001	3	7
UCEC	C1orf116 →	+0.821	+1.123	<.001	<.001	3	6
GBM	ANXA2 →	+0.604	+1.057	<.001	<.001	3	6
LSCC	TJP3 →	+0.537	+1.451	<.001	<.001	3	5
GBM	S100A10 →	+0.599	+1.052	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,457 associations by consensus.

GPRC5A vs GPRC5A_S301 — GBM

Explore this scatter interactively →