GPRC5A

Across TCGA cell cohorts, GPRC5A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,847 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GPRC5A-associated GO terms across cancer lineages are Wound healing, Positive regulation of plasma membrane repair, and Plasma membrane organization. Each is linked with GPRC5A in more than 13 cancer types. Because this analysis shows association rather than direction, both GPRC5A-to-partner and partner-to-GPRC5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Wound healing grouped by GPRC5A-low versus GPRC5A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5A→partner) and Y-score (partner→GPRC5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Wound healing →	+0.108	+2.338	<.001	<.001	3	14
BONE	Positive regulation of plasma membrane repair →	+0.281	+2.305	<.001	<.001	3	14
BONE	Plasma membrane organization →	+0.133	+2.188	<.001	<.001	3	13
PANCREAS	Negative regulation of actin filament polymerization →	+0.231	+2.568	<.001	<.001	3	13
LUNG_NSCLC_LUAD	Regulation of actin filament depolymerization →	+0.148	+2.717	<.001	<.001	3	13
LIVER	Positive regulation of protein localization to membrane →	+0.114	+3.994	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,847 associations by consensus.

Wound healing by GPRC5A expression — BONE

Explore this box plot interactively →