GPRASP2

Across TCGA cell cohorts, GPRASP2 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPRASP2-associated genes across cancer lineages are PNMA6F, GALR3, and ELAC1. Each is linked with GPRASP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPRASP2-to-partner and partner-to-GPRASP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNMA6F grouped by GPRASP2-low versus GPRASP2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRASP2→partner) and Y-score (partner→GPRASP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PNMA6F →	+0.012	+4.887	<.001	.009	3	1
LARGE_INTESTINE	GALR3 →	+0.127	+3.602	<.001	.005	3	1
LARGE_INTESTINE	ELAC1 →	+0.833	+3.215	<.001	.009	3	1
LARGE_INTESTINE	PRR35 →	+0.059	+3.472	.003	.005	3	1
LARGE_INTESTINE	NRTN →	+0.903	+3.064	.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.010	+2.977	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

PNMA6F by GPRASP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →