Across TCGA patient cohorts, GPR89B mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR89B-associated genes across cancer lineages are 4E-BP1, eIF4E, and MEK1. Each is linked with GPR89B in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR89B-to-partner and partner-to-GPR89B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR89B→partner) and Y-score (partner→GPR89B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.410	+3.321	<.001	.009	3	2
UCEC	eIF4E →	+0.203	+3.335	.014	.005	3	1
UCEC	MEK1 →	+0.452	+3.169	.001	<.001	3	1
UCEC	MSH2 →	-0.280	-2.295	.001	.033	3	1
UCEC	PCNA →	+0.239	+2.459	.004	.018	3	1
UCEC	PDCD4 →	-0.506	-3.321	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

GPR89B survival (RNA) · tumor vs normal (RNA) · all GPR89B data types