GPR89A

Across TCGA patient cohorts, GPR89A protein abundance is significantly associated with the RNA expression of many other genes, with 345 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR89A-associated genes across cancer lineages are PDGFB, SLC52A3, and CDS2. Each is linked with GPR89A in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR89A-to-partner and partner-to-GPR89A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR89A versus PDGFB in GBM, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR89A→partner) and Y-score (partner→GPR89A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PDGFB →	+0.699	+0.844	<.001	.001	3	1
GBM	SLC52A3 →	+0.979	+0.826	<.001	.001	3	1
GBM	CDS2 →	+0.662	+0.697	.004	.009	3	1
GBM	CCM2L →	+0.641	+1.042	.001	.005	3	1
GBM	ATP11C →	-0.801	-1.134	<.001	.009	3	1
GBM	SEMA3G →	+1.240	+1.155	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 345 associations by consensus.

GPR89A vs PDGFB — GBM

Explore this scatter interactively →