GPR89A

Across TCGA patient cohorts, GPR89A mutation is significantly associated with the RNA expression of many other genes, with 1,511 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR89A-associated genes across cancer lineages are TRBV23OR9-2, IGHD1-1, and TUBB8P5. Each is linked with GPR89A in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR89A-to-partner and partner-to-GPR89A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRBV23OR9-2 grouped by GPR89A-low versus GPR89A-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR89A→partner) and Y-score (partner→GPR89A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TRBV23OR9-2 →	+0.292	+4.970	<.001	.005	3	2
UCEC	IGHD1-1 →	+0.738	+3.598	<.001	.002	3	2
UCEC	TUBB8P5 →	+0.612	+2.230	<.001	.005	3	2
BRCA	LONRF2P5 →	+0.341	+5.971	<.001	.002	3	1
SKCM	RNA5SP483 →	+0.472	+4.188	<.001	.009	3	1
SKCM	RNU6-1158P →	+0.267	+5.199	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,511 associations by consensus.

TRBV23OR9-2 by GPR89A expression — SKCM

Explore this box plot interactively →