GPR89A

Across TCGA cell cohorts, GPR89A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR89A-associated genes across cancer lineages are OR9G1, RGPD4, and TEX53. Each is linked with GPR89A in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR89A-to-partner and partner-to-GPR89A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9G1 grouped by GPR89A-low versus GPR89A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR89A→partner) and Y-score (partner→GPR89A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR9G1 →	+0.213	+3.874	<.001	.005	3	1
BLOOD_Leukemia	RGPD4 →	+0.427	+4.037	<.001	.004	3	1
LARGE_INTESTINE	TEX53 →	+0.105	+3.684	<.001	.006	3	1
LARGE_INTESTINE	ADAM7 →	+0.005	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR9G1 by GPR89A expression — BLOOD_Leukemia

Explore this box plot interactively →