GPR88

Across TCGA cell cohorts, GPR88 RNA expression is significantly associated with the go_rna of many other GO terms, with 713 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR88-associated GO terms across cancer lineages are Potassium ion transport, Regulation of RNA export from nucleus, and Negative regulation of myoblast fusion. Each is linked with GPR88 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR88-to-partner and partner-to-GPR88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Potassium ion transport grouped by GPR88-low versus GPR88-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR88→partner) and Y-score (partner→GPR88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Potassium ion transport →	-0.038	-0.020	<.001	.008	3	5
PANCREAS	Regulation of RNA export from nucleus →	+0.072	+0.004	.005	.003	2	5
SKIN	Negative regulation of myoblast fusion →	+0.078	+0.038	<.001	.008	3	4
SKIN	Amyloid fibril formation →	+0.068	+0.020	<.001	.009	3	4
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.077	+0.038	<.001	.008	3	4
SOFT_TISSUE	Regulation of protein localization to Cajal body →	+0.039	+0.044	.003	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 713 associations by consensus.

Potassium ion transport by GPR88 expression — SKIN

Explore this box plot interactively →